Animal & Bioscience Research Department Staff

Name:	Dr. David J. Lynn (M.Sc., Ph.D.) Group Leader - Systems Biology/Immunology
Contact Details:	Animal & Grassland Research and Innovation Centre, Teagasc, Grange, Dunsany, Co. Meath, Ireland. +353 (0)46 9026729 david.lynn@teagasc.ie
Research Interests:	Systems Biology Network Biology Bioinformatics Innate Immunity Infectious Disease Population Genetics/Evolution Mastitis TB
Selected Publications:	View selected publications
Equipment / Technologies:	Computational biology, RNAseq, microRNAs
Current Role / Title:	Vision Appointment in Computational Biology
Current Projects:	PRIMES. Protein interaction machines in oncogenic EGF receptor signalling. InnateDB (www.innatedb.com) a systems biology platform for the analysis of mammalian signalling. Enabling bovine systems biology in the post-genomics era. Transcriptional profiling (RNAseq/miRNAseq) of the host response to mastitis pathogens. Investigating the role of miRNA regulatory networks in M. bovis infected alveolar macrophages. Genome-wide association studies of milk production traits and SCC. Bovine genetic variation and disease. Systems biology approaches to profiling the innate immune response to infection in other species (human/mouse)
Education:	Postdoctoral Experience: Jan 07 – Aug 09 Postdoctoral Research Associate, Department of Molecular Biology & Biochemistry, Simon Fraser University, Burnaby, Greater Vancouver, British Columbia, Canada. Honorary Research Associate, The Centre for Microbial Diseases & Immunity Research, University of British Columbia, Vancouver, British Columbia, Canada Mar 04 – Dec 06 Postdoctoral Fellow, Population Genetics Laboratory, Smurfit Institute of Genetics, Trinity College Dublin, Dublin 2, Ireland. Education: 2001 - 2004 Ph.D. (Bioinformatics & Innate Immunology), Department of Medicine, University College Dublin, & The Education & Research Centre, St. Vincent’s University Hospital, Dublin 4, Ireland. 2002 – 2003 Postgraduate Certificate in Research Methods (Statistics), Department of Statistics, University College Dublin, Dublin 4, Ireland. 2000 - 2001 Research M.Sc. Biology (Bioinformatics), Department of Biology, University of Ottawa, Ottawa, Ontario, Canada. 1996 - 2000 B.A. Natural Sciences - Moderatorship in Genetics, Smurfit Institute of Genetics, Trinity College Dublin, Dublin 2, Ireland.
Collaborations:	Prof. Walter Kolch, Systems Biology Ireland. PRIMES. Protein interaction machines in oncogenic EGF receptor signalling. Dr. Kurt Zuelke, Dr. Tim Reinhardt, Dr. John Lippolis & Dr. Tad Sonstegard: USDA ARS, USA. Systems biology of bovine mastitis infections. International Molecular Exchange Consortium (IMEx)/European Bioinformatics Institute, UK: Molecular interaction data curation. Prof. Dan Bradley: Trinity College Dublin, Dublin & Dr. Donagh Berry, Teagasc Moorepark, Fermoy, Ireland. Bovine genetic variation and disease. Prof. David MacHugh: University College Dublin, Ireland. MicroRNA regulatory networks in the host response to TB. Prof. Cliona O'Farrelly: Trinity College Dublin, Ireland. RNA-seq approaches to investigating the host response to bovine mastitis. Prof. Fiona Brinkman & Prof. Bob Hancock: Simon Fraser University & University of British Columbia, Vancouver, Canada. InnateDB - facilitating systems level analyses of innate immunity. Dr. Cameron Simmons: Oxford University Clinical Research Unit, Vietnam. Transcriptional profiling of Dengue fever patients. Dr. Tom Freeman: Roslin Institute, Edinburgh, Scotland. Macrophage pathway curation. Prof. Gordon Dougan & Fernanda Schreiber: Wellcome Trust Sanger Institute, Hinxton, UK. Systems biology analyses of human infections. Melita Gordon: University of Liverpool, Liverpool, UK. Pathway and network analysis of NTS in HIV+ patients in Malawi. Prof. Bill Jacobs & Dr. Dee Dao: Albert Einstein College of Medicine, New York, USA. Analysis of the host response to TB in a murine model.
Presentations:	View selected presentations
Students:	Theodosia Charitou Amir Foroushani Brian Meredith Nathan Lawless Peter Vegh
Postdocs & staff:	Dr. Heather Wiencko (SFI Postdoc) Dr. Kenneth Bryan (PRIMES Senior Postdoc) Mr. Manuel Bernal Llinares (PRIMES Database Developer)