Linda Giblin
Research OfficerResearch Interests
Linda Giblin is a Senior Research Officer and Molecular/Cellular Biologist investigating Food Bioavailability & Bioactivity. She is interested in food derived bioactive peptides, their digestion and bioavailability. She has developed a number of cellular assays to assess bioactivity of food peptides and has recently focused her attention on Intestinal Barrier Function for different life stages.
- Intestinal Barrier Health (Infant & Adult)
- Protein quality (Digestible Indispensable Amino Acid Score, Bioavailability)
- Life Stage Nutrition: Foods for pregnant women, foods for elderly, foods for the infant
- Foods for satiety, adipocyte and muscle health
Current Projects
- VistaMilk-16RC335, Science Foundation Ireland & Irish Department of Agriculture, Food & Marine, Funded Investigator,
- Infotech-2019R495, Department of Agriculture, Food & Marine, collaborator
- TOMI-15F604, Department of Agriculture, Food & Marine, Co-ordinator & PI
- MilkEVs-17F234, Department of Agriculture, Food & Marine, collaborator
- BioProtein-MDBY0360, Teagasc, Co-ordinator & PI
- INFBAR-1370, Teagasc, Co-ordinator & PI
- FoodBIBS-EI-MF2018-0151, EU Horizon2020 Marie Sklodowska Curie, Co-ordinator & PI
- UPROTEIN-2019PROG702, Department of Agriculture, Food & Marine, Task leader
- Cyclone-MDBY1225, Private Sector, Coordinator
- APC-HDH-Health MDBY1010, Private Sector, Collaborator
- EAT4AGE-2020HDHL101, EU Horizon2020 Joint Programme Initiative & Department of Agriculture, Food & Marine
- GlycoMatch Maker-898013, EU Horizon2020-MSCA-IF-2019 - Marie Sklodowska Curie, collaborator
- OptimA-RISAM, Munster Technology University
Education
Ph.D. University College Cork, Ireland
B.Sc. Biotechology, Dublin City University, Ireland
Professional Membership
Associate Editor of Journal of Functional Food
Editorial Board Member of Journal of Dairy Science
Editorial Board Member of Trends in Food Science & Technology
INFOGEST (Core group member & working group 3 leader)
INFOGEST-UNGAP partnership (working group 4 leader)
NutRedOx (Core group member & working group 4 co-leader)
American Dairy Science Foundation
Nutrition Society
orcid.org/0000-0002-9354-3121, ResearchID P-2436-2016
- Kondrashina A., Brodkorb A. and Giblin L. 2021. Sodium butyrate converts Caco-2 monolayers into a leaky but healthy intestinal barrier resembling that of a newborn infant. Food & Function, 12, 5066-5076. DOI 10.1039/d1fo00519g. Impact factor 5.396
- Bavaro S.L., Mamone G., Picariello G., Callanan M. J., Chen Y., Brodkorb A. and Giblin L. 2021. Thermal or membrane processing for Infant Milk Formula: Effects on protein digestion and integrity of the intestinal barrier. Food Chem. 347: 129019. DOI: 10.1016/j.foodchem.2021.129019. Impact Factor 7.541
- Nychyk O., Barton W., Rudolf A. M., Boscaini S., Walsh A., Bastiaanssen T. F. S., Giblin L., Cormican P., Chen L., Piotrowicz Y., Derous D., Fanning A., Yin X., Grant J., Melgar S., Brennan L., Mitchell S. E., Cryan J. F., Wang J., Cotter P. D., Speakman,J. R. and Nilaweera K. N. 2021. Protein quality and quantity influence the effect of dietary fat on weight gain and tissue partitioning via host-microbiota changes, Cell Reports, 35, 109093. IF 8.1
- Heffernan S, Giblin L., O'Brien N. 2021. Assessment of the biological activity of fish muscle protein hydrolysates using in vitro model systems. Food Chem. doi:10.1016/j.foodchem.2021.129852. Impact Factor 7.541
- Heffernan S., Harnedy-Rothwell P.A., Gite S., Whooley J., Giblin L. Fitzgerald D.J. and O’Brien N.M. 2021. Blue Whiting Protein Hydrolysates Exhibit Antioxidant and Immunomodulatory Activities in Stimulated Murine RAW264.7 Cells. Appl. Sci. 11(20), 9762; doi.org/10.3390/app11209762.
- Chen Y., Callanan M., Shanahan C., Tobin J., Gamon L.F., Davies M.J., Linda Giblin L. and Brodkorb A. 2021. The Use of Membrane Filtration to Increase Native Whey Proteins in Infant Formula. airy 2021, 2(4), 515-529; doi.org/10.3390/dairy2040041.
- Ariadna Gasa-Falcon A., Arranz E., Odriozola-Serrano I., Martín-Belloso O. and Giblin L. 2020. Delivery of β-carotene to the in vitro intestinal barrier using nanoemulsions with lecithin or sodium caseinate as emulsifiers. LWT-Food Science and Technology. 135: 110059. . Impact Factor 4.952
- Gilmartin S, O'Brien N, Giblin L. 2020. Whey for Sarcopenia; Can Whey Peptides, Hydrolysates or Proteins Play a Beneficial Role? Foods. 2020 Jun 5;9(6):750. Impact Factor 4.350
- Kondrashina A., Brodkorb A., Giblin L. 2020. Dairy-derived peptides for satiety. Journal of Functional Foods. 66: 103801. . Impact Factor 4.451
- Arranz, E., A. R. Corrochano, C. Shanahan, M. Villalva, L. Jaime, S. Santoyo, M. J. Callanan, E. Murphy, and L. Giblin. 2019. Antioxidant activity and characterization of whey protein-based beverages: Effect of shelf life and gastrointestinal transit on bioactivity. Innovative Food Science and Emerging Technologies 57: 102209. Impact Factor 5.916
- Corrochano, A. R., Y. Saricay, E. Arranz, P. M. Kelly, V. Buckin, and L. Giblin. 2019. Comparison of antioxidant activities of bovine whey proteins before and after simulated gastrointestinal digestion. Journal of Dairy Science 102(1):54-67. Impact Factor 4.034
- Chen, Z. F., A. Kondrashina, I. Greco, L. F. Gamon, M. N. Lund, L. Giblin and M. J. Davies. 2019. Effects of Protein-Derived Amino Acid Modification Products Present in Infant Formula on Metabolic Function, Oxidative Stress, and Intestinal Permeability in Cell Models. Journal of Agricultural and Food Chemistry 67(19):5634-5646. Impact Factor 5.279.
- A. R. Corrochano, A. Ferraretto, E. Arranz, M. Stuknyte, M. Bottani, P. M. O'Connor, P. M. Kelly, I. De Noni, V. Buckin and L. Giblin. 2019. Bovine whey peptides transit the intestinal barrier to reduce oxidative stress in muscle cells. Food Chemistry, 288, 306-314. Impact Factor 7.541.
- E. Arranz, A. R. Corrochano, C. Shanahan, M. Villalva, L. Jaime, S. Santoyo, M. J. Callanan, E. Murphy and L. Giblin. 2019. Antioxidant activity and characterization of whey protein-based beverages: Effect of shelf life and gastrointestinal transit on bioactivity. Innov Food Sci Emerg, 57. Impact Factor 5.916.
- A. Kondrashina, D. Papkovsky and L. Giblin. 2018. Physiological Gut Oxygenation Alters GLP-1 Secretion from the Enteroendocrine Cell Line STC-1. Molecular Nutrition & Food Research, 62. Impact Factor 5.914
Linda has supervised 9 PhD and 11 MSc postgraduates to completion, and mentored 10 post-doctoral scientists. Her lab currently consists of 10 PhD students.