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Kieran Meade

Research Officer - Immunogenetics & Animal Health

Research Interests

My research program focuses on understanding the innate immune response in order to develop better strategies to enhance protection against disease.

  • Specific focus on neutrophils, γδ T cells and the role host defence peptides (HDPs) in male and female immunology
  • Natural mechanisms of disease resistance
  • Neonatal, intestinal and uterine immunity
  • Epigenetic regulation of immunity

Current Projects

Reproductive immunology

  • Host-pathogen interplay and bacterial clearance post-partum
  • Regulation of β-Defensin and Cathelicidin (host defence peptides) expression
  • Role of HDP in reproduction and fertility

Mechanisms of Immunity

  • Epigenetics and bovine tuberculosis
  • Improved diagnosis of Mycobacterium avium paratuberculosis
  • SNP discovery in β-Defensin and Cathelicidin genes
  • Neutrophil and γδ T cell biology

Education

Bachelor of Agriculture in Animal Science, University College Dublin.

Ph.D. in Molecular genetics, University College Dublin included work in Michigan State University and ILRI, Kenya. 

Postdoctoral research in St. Vincent’s University Hospital, Dublin and School of Biochemistry and Immunology, Trinity College Dublin.

Professional Membership

Irish Society of Immunology (ISI)

Adjunct Assistant Professor in Immunology, Trinity College Dublin.

Currently secretary of the Association of Veterinary Teaching and Research work (AVTRW)

For all peer-reviewed publications please see: https://www.ncbi.nlm.nih.gov/pubmed/?term=Meade+KG

Anne-Barry Reidy, B. Sc 
– Regulation and Expression of novel Defensin genes in Cattle

Amy Brewer, B.Sc, M.Sc
- Improved diagnostics for endometritis in the post-partum dairy cow

Paul Kelly, M.Sc
- Regulation of endometrial immune responses in the post-partum dairy cow

Megan O’ Brien, M.Sc
- Interleukin 8 haplotype and their role in neonatal disease susceptibility