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Orla O'Sullivan

Research Officer

Research Interests

Research interests include compostional analysis of microbial communities, metagenomics and metabolomics of microbial communities, genome sequencing and annotation, comparative genomics, homology modelling and structure prediction, protein-peptide binding and bioactive discovery.

Education

B.Sc. (Hons.) Biochemistry 2000 National University Ireland, Cork

PhD Bioinformatics 2004 National University Ireland, Cork.

Rea MC, Dobson A, O'Sullivan O, Crispie F, Fouhy F, Cotter PD, Shanahan F, Kiely B, Hill C, Ross RP. Effect of broad- and narrow-spectrum antimicrobials on Clostridium difficile and microbial diversity in a model of the distal colon. Proc Natl Acad Sci U S A. 2010 Jun 29.

Claesson MJ, O'Sullivan O, Wang Q, Nikkilä J, Marchesi JR, Smidt H, de Vos WM, Ross RP, O'Toole PW. Comparative analysis of pyrosequencing and a phylogenetic microarray for exploring microbial community structures in the human distal intestine. PLoS One. 2009 Aug 20;4(8):e6669.

O'Sullivan O, O'Callaghan J, Sangrador-Vegas A, McAuliffe O, Slattery L, Kaleta P, Callanan M, Fitzgerald GF, Ross RP, Beresford T. Comparative genomics of lactic acid bacteria reveals a niche-specific gene set. BMC Microbiol. 2009 Mar 5;9:50.

O'Sullivan O, Wallace IM, Higgins DG, Notredame C. M-Coffee: combining multiple sequence alignment methods with T-Coffee. Nucleic Acids Res. 2006 3;34(6):1692-9.

O'Sullivan O, Suhre K, Abergel C, Higgins DG, Notredame C. 3DCoffee: combining protein sequences and structures within multiple sequence alignments. J Mol Biol. 2004 Jul 2;340(2):385-95.