Work Package 2a State-of-the-Art

• A comprehensive literature review was conducted, making use of the internet and available abstracts databases. The British library Document Supply service and inter-library loans were being extensively used to obtain hardcopies of the literature.
• All literature collected was entered into a database (EndNote) and filed.
• A review of unpublished work undertaken in Ireland was carried out
• NATFOREX database was interrogated to source existing national trials to visit
• Discussions with experts at these visits was also used to inform WP2b, WP2c, WP2d and WP2e. There are also possible linkages with WP3a.